L-Tyrosine is an amino acid (building block of protein) that is "conditionally essential," as generally it must be supplied by the diet, although it can be produced from the essential amino acid L-Phenylalanine (a process dependent upon vitamin B-6). (L-tyrosine is essential for individuals with phenoketonuria, who cannot produce L-Tyrosine from L-Phenylalanine.) L-Tyrosine is the precursor to the thyroid hormones, as well the catecholamines, dopamine, norepinephrine and epinephrine. As such, deficiency can have far-reaching affects on metabolic rate and neural regulation of the sympathetic nervous system(1-3), including central effects on mood and memory(4, 5). In particular, supplementing with L-Tyrosine may enhance arousal and therefore performance during high intensity exercise, such as weight training (6). During a fat-loss regimen that includes thermogenic supplements such as ephedrine or Green Tea Extract, L-Tyrosine may enhance the anorectic (appetite suppressing) actions of these supplements(7).
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